| scheußlich | abominable atrocious |
| Schlusslicht | tail light taillight tail ender tail lamp tailender |
| Scheißpech | tough shit |
| schauerlich | creepy |
| schließlich | eventually finally after all |
| süßlich | saccharine |
| Schlich | wile |
| Schluckloch | sinkhole |
| schimpflich | deplorable |
| schmerzlich | poignant painful |
| schmählich | ignominious |
| schusssicher | bulletproof |
| schwächlich | delicate fragile feeble |
| schwärzlich | blackish |
| Scheich | sheik shaikh shaykh sheikh |
| Scheusal | monster beast |
| Schlupfloch | loophole |
| Schlussstrich | final stroke |
| Schlüsselloch | keyhole keyway |
| Schössling | shoot |